January 24, 2006

Minutes of January Board Meeting

by Gloria. D. Jahnke, GEMS Secretary
January 11, 2006
CIIT

1. President Les Recio called the Board to order at 3:00 p.m. The following members were present: Les Recio, Greg Stuart, Susan Ross, Gloria Jahnke, Janice Allen, Rose Anne McGee, Cindy Innes, Jayne Boyer, Susan Oxendine, and Errol Zeiger. An assortment of cookies and soft drinks were made available to the participants by the host, Susan Ross and CIIT.

2. Susan Ross presented the treasurer’s report and provided a handout of the GEMS Financial Report for January 11, 2006. The balance in the checking and money market accounts were reported. Gloria Jahnke reported that a thank you letter acknowledging NIEHS’ conference contribution had been sent to Ms. Ann M. Parnow, coordinator, government programs, at Courtesy Associates in Washington, DC. Also enclosed with the letter was the GEMS 2005 fall meeting summary and completed W-9 tax form.

3. Membership Approval of GEMS By-Laws. Errol Zeiger has completed an update of the GEMS By-Laws and they are ready for approval by the membership. It was decided that a pdf file would be prepared of the revised by-laws along with a letter/ballot to the membership. The letter would provide choices of acceptance of all changes, non- acceptance, and partial acceptance with space for comments. The membership voting would be through a global email submitted by the webmaster, Frank Stack. A time frame for receipt of membership response would be with the email. It was proposed that a two week timeframe be used with a reminder sent at one week.

4. 2006 Spring Meeting. Discussion of the 2006 Spring Meeting was lead by Greg Stuart. He is in the process of contacting the NC Center for Biotechnology to schedule the meeting for the last week in April. He provided a handout to the Board listing potential meeting topics. Some of the topics were not relevant to the GEMS and were deleted: Air Pollution and Human Health, Infectious Diseases, and Clinical Research Programs. The topics (see below) of Antimutagenic Mechanisms of Chemopreventive Agents (7 votes) and Oxidative Damage & Stress (7 votes) received the most votes. It was proposed by Les that the topic of “Antimutagenic Mechanisms” be used. This subject encompasses a broader area, e.g., oxidative stress, DNA repair, phase two metabolism, and holistic medicine. It was suggested that someone in Tom Kunkel’s laboratory and a research scientist from UNC, Rudolph Salganik, could be speakers. The possibility of GEMS hosting a career lunch in conjunction with the Spring meeting was discussed. Gloria will talk with Jane Allen who had chaired last year’s effort about the usefulness of this venue. It was suggested that some GEMS members could be identified as available to answer career questions informally at the spring meeting and via email.

5. GEMS 25th Anniversary. The 25th fall meeting of GEMS will be in 2007. October, 1983 was the first annual meeting, so the 2007 Fall meeting will be the 25th. RoseAnne McGee suggested that for the 25th anniversary of GEMS, there be a 1 ½ day scientific meeting and reunion. EMS members and GEMS past presidents would be invited and a hotel would host the meeting. There would need to be a change in venue for this fall meeting, such as using the Sheraton Hotel or Holiday Inn at Research Triangle Park. Janice Allen and Rose Anne McGee volunteered to provide information to the BOD regarding the local venues.

6. Corporate Sponsor Representative. It is uncertain whether the current GEMS corporate representative will continue for 2006 and the Board discussed a potential replacement. Les will confirm whether Rob plans to continue to serve as GEMS corporate representative. Les will also ask for feedback on responses from vendors from the 2005 fall meeting.

7. GEMS Newsletter. A replacement for newsletter editor was discussed. It was proposed that the content of the newsletter could be handled through the GEMS blog and/or website providing that the membership be alerted that this information is available and that the template for the GEMS Newsletter be used. Items covered in the newsletter are: list of officers, a list of corporate sponsors, a meeting summary from the travel award recipient, pictures from meetings, meeting information, letter from the president-elect, information on meeting registration, abstract submission, and the draft meeting program.

8. The next board meeting will be February 23, 2006 at 3 PM at CIIT


Fall Meeting Topics and Votes

7 Antimutagenic Mechanisms of Chemopreventive Agents
7 Oxidative Damage & Stress
4 Individual Variation In Health & Disease.
4 In vitro Models of DNA Damage, Mutagenesis & Repair (or Prevention)
3 Diet & Cancer
3 Mitochondrial DNA Damage & Repair
3 RNA (Ribonucleic Acid) Technology
2 Mouse Models of Disease
2 Scientific Fraud & the Integrity of Science
2 Systems/Integrative Biology
1 Environmental Factors Influencing Development
1 Gene Interactions During Mammalian Development
1 Genetic Consequences of Environmental Exposures
1 Mouse Models of Mutagenesis & Carcinogenesis
1 Mouse Models In Toxicology
0 Alternatives to Animal Testing in Toxicology
0 Cell Imaging
0 Chromatin Modifications & Cellular Responses
0 Developmental Toxicology
0 Gene Therapy
0 Genotoxicology Models
0 Global Testing Requirements
0 Health of Children (Sensitive Populations)
0 Imprinting
0 Microarrays
0 Mitochondria

January 12, 2006

GEMS Spring Meeting 2006: Call For Speakers


An open invitation from Greg Stuart, GEMS President-Elect

Greetings! I am planning the date and agenda for the upcoming GEMS Spring Meeting, to be held at the North Carolina Biotechnology Center in April 2006.

I have tentatively booked the N.C.B.C. for Monday April 24, 2006. Other possible dates are May 01, 05, 09, 10, 11, or 12. However, unless anyone has a strong opinion in favor of another date, let's plan to meet on April 24, 2006.

At today's Board Meeting, we decided (majority vote) that the theme of the meeting would be "Antimutagenesis and Anticarcinogenesis" (tentative title). This topic broadly encompasses many areas of interest to GEMS members, including:

- diet & cancer e.g. dietary antimutagens, antioxidants, mutagens
- oxidative damage; reactive oxygen species
- individual susceptibility, e.g. SNPs; phase I and II metabolism (P450s; GSTs)
- DNA repair
- inhibition of tumor angiogenesis; estrogen receptor modulators; apoptosis

At this time I would ask that people email me (stuart@niehs.nih.gov) any suggestions that they might have for Speakers, plus any additional comments.

I look forward to your responses, and/or meeting you at the Spring Meeting!

Sincerely yours,

Greg Stuart
stuart@niehs.nih.gov
gstuart1@nc.rr.com

January 09, 2006

Planning for Spring Meeting

by Greg Stuart, President-Elect

Hello and Happy New Year 2006! This is an update to my email circulated to the BOD on Dec. 22, 2005 regarding planning for the Spring 2006 Meeting, which is generally held each April. As requested previously, please respond to this post and I will collect and summarize the responses at the next GEMS BOD meeting.
NEXT GEMS BOD MEETING: Tentative dates for the GEMS BOD meeting were Jan. 10 or 11 at CIIT. Who can attend Wed. Jan. 11, 2006? Or should we schedule a date later in the month (e.g., Wed. Jan. 18), allowing time for more feedback from the BOD? My primary concern is selecting a topic for the Spring 2006 meeting. Ideally, I would like the BOD to vote on a Spring Meeting topic at the next BOD meeting, and also select potential meeting dates (any Tues., Wed. or Thurs. in the 2nd, 3rd or 4th weeks of April 2006?) for presentation to the N.C. Biotechnology Center.


Non-GEMS Dates-of-Interest:
  • Feb.16, 2006: N.C. SOT Meeting, 12:30-5:00 pm at U.S. EPA, RTP
  • March 5-9, 2206: SOT
  • Mar. 26-28, 2006: IACUC (Institutional Animal Care and Use Committees) Conference, Boston
  • Mar. 26-30, 2006: American Chemical Society
  • Mar. 13-16, 2006: Association for Environmental Health & Sciences
  • Apr. 01-05, 2006: AACR (American Association for Cancer Research) meeting (Townsend & Miller labs will be attending)
  • Apr. 14, 2006: Good Friday
  • Apr. 17, 2006: Easter Monday

*** POTENTIAL SPRING 2006 MEETING TOPICS ***
SUGGESTIONS FROM GEMS BOD (Dec. 22, 2005 - Jan. 03, 2006):
  • JB: Of the topics listed, I like: Environmental &/or Dietary influences on Disease; Genetic Consequences of Environmental Exposure; Genotoxicity Models. What about focusing on one type of cancer: Breast, colon, prostate, skin??
  • CI: My vote would be RNA World (with a different title) or Epigenetics, which sounds like it would include some Environmental & Dietary influences on disease.
  • EZ: Given the recent, and ongoing, headlines relating to scientific fraud and the integrity of science and its practitioners, this may be a good time to arrange a conference relating to these topics. There are a number of local people with the appropriate credentials and interests for such a conference.
PREVIOUS GEMS MEETING TOPICS:
  • Fall 2002 (Oct. 24): "The Science of Bioterrorism."
  • Spring 2003 (Apr. 14): "Molecular Epidemiology of Cancer." Speakers: Dr. Peter Inskip (NCI); Dr. Judy Mumford (EPA); Dr. Jennifer Hu (WFUSM); Dr. Robert Millikan (UNC-CH); Dr. Doug Bell (NIEHS); Dr. David Schwartz (Duke University).
  • Fall 2003 (Nov. 05): “DNA Damage and Repair.” Speakers: Dr. Michael Resnick (NIEHS); Dr. James A. Swenberg (UNC); Dr. Karin Drotschmann (WFUSM); Dr. Kenneth N. Kreuzer (DUMC). Plus: Student & Post-Doctoral Speakers.
  • Spring 2004 (Apr. 22): "RNAi and Silencing of Genes." Speakers: Dr. Caplen (NCI) ?; ...
  • Fall 2004 (Nov. 10; 22nd Annual Meeting): "DNA Methylation and its Toxicological Consequences." [Epigenetics] Speakers: Dr. Jay Goodman (Michigan State University); Dr. Trevor Archer (NIEHS) - Did not present?!; Dr. Randy Jirtle (Duke University School of Medicine). Student & Post-Doctoral Speakers: Rebecca Clewell (CIIT); Isaac Snowhite (Wake Forest); William Ward (EPA); Cynthia Innes (NIEHS); Beth Van Emburgh (WFUMC?).
  • Spring 2005 (Apr. 12): "Stem Cells: Biology & Toxicological Relevance." Speakers: Dr. Brigid Hogan (Duke University); Dr. Lola Reid (UNC-CH); Dr. Tannistha Reya (Duke University); Dr. James Sherley (MIT); Ms. Carole Tempus (NIEHS); Dr. Julian Preston (EPA). Plus: Student & Post-Doctoral Speakers.
  • Fall 2005 (Oct. 26): "Genetics of Aging." Speakers: Dr. Olga Sedelnikova (NCI); Dr. Christopher Corton (EPA). Student & Post-doctoral Speakers: Stephanie Dance; Wade Lehmann; Sharon Oxendine; Ashley Rivenbark; Carol Swartz; Dana Upton.
PAST SUGGESTED MEETING TOPICS: From the GEMS Board Meeting Minutes, December 18, 2003: By vote of the board, the 2004 meeting topics were selected from the following list.
  • Mutations in Mitochondrial DNA
  • RNAi and Silencing of Genes - DONE
  • Imprinting
  • Mouse Models of Disease
  • Apoptosis
  • Developmental Toxicology
  • Infectious Disease and Toxic Responses (e.g., Herpes, Papilloma Viruses)
  • Mutation Phenotypes and Aging
  • Oxidative Stress and Free Radicals
  • Biological Basis of Aging - DONE
  • Alternative to Animal Testing in Toxicology